One-of-its-Kind Study Discovers over 100 Genes Involved in Schizophrenia

In a breakthrough revelation, researchers have found 128 genes involved in schizophrenia, a brain disorder. In a decade-long research, 300 scientists from 35 nations came to a conclusion that a cure to this problem would not be achievable with a single treatment.

It has been said so as problem is scattered in many genes related to learning, memory, brain signaling and immune system.

Steve McCarroll, head of genetics at the Stanley Center for Psychiatric Research at the Broad Institute of the Massachusetts Institute of Technology and Harvard in Cambridge, said the research will help them broaden their knowledge base with regard to the disease.

"Once you have the parts, you can start fitting them together, then you can identify ways to improve the outcomes in that system", asserted McCarroll. The research findings help in having a deeper view of the problem and knowing how and why the disease has formed.

In the study, researchers assessed the genomes of 36,989 schizophrenia patients and compared the result with 113,075 healthy volunteers. Researchers noted connections in the way neurons communicate with other neurons during the learning process.

The new study has also confirmed the long-suspected link to dopamine, a hormone acting as a signaler between cells. The research findings point to biological mechanisms and pathways that may be causing schizophrenia and could lead to new approaches to treat the disease.

Schizophrenia affects one in every 100 people. Its symptoms include hallucinations, delusions and disordered thinking. The disease generally occurs in teenage and early 20s.


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