Researchers Create ‘Biological Pacemaker’ Cells

A breakthrough revelation has been made as researchers have been able to transform ordinary cardiac muscle cells into specialized cells that provide quick heartbeat. The process was possible due to a gene therapy.

As per researchers, the procedure could one day become an alternative to implanted electronic pacemakers. An experiment was carried out in which 16 pigs having the condition called heart block were taken. The condition reduces the pace of heartbeat significantly.

Researchers injected a human gene into a small place of the heart's pumping chambers. In the next step, researchers reprogrammed heart muscle cells into a type of cells that emit electrical impulses. With the help of impulses, heartbeat pace increased.

During this process, cardiologists at Cedars-Sinai Heart Institute in Los Angeles developed 'biological pacemaker' cells. These cells helped in restoring normal heartbeat in the pigs.

"This development heralds a new era of gene therapy where genes are used not only to correct a deficiency disorder but actually to convert one type of cell into another to treat disease", affirmed Dr. Eduardo, Director of the Cedars-Sinai Heart Institute.

Researchers shared pigs' hearts are very similar to human hearts. Dr. Eugenio Cingolani, Director of the institute's Cardiogenetics-Familial Arrhythmia Clinic, said more clinical trials on animals will be carried out. If all goes well, then they expect to begin trials in humans within three years.

It is expected that the procedure will help people living with heart rhythm disorders who cannot use a pacemaker owing to device-related complications, including infection.


AustrianTribune Specials

Hawai'i Space Exploration and Simulation (HI-SEAS) mission, headed by its crew members returned to Earth after spending four months on simulated Mars early Friday morning.

This was the very first group to spend a lot of time in farfetched...

Most Popular

On Thursday, the Russian space agency announced that...

European bat has been found to use the scattered...

Rosas Cruz, 25, suffering from tuberculosis, went...

The closure of the Kenai River king salmon fishery has...

Automotive News

  • GM announces six recalls covering 717,950 vehicles in US
  • GM issues "stop delivery order" to dealers to stop selling Cadillac CTS and SRX models
  • IHS Automotive: SUVs and crossovers are outselling sedans in US market
  • JLR to develop much ‘smarter’ cars
  • Honda’s US regional recall due to airbag issue expanded to include California

UK News

  • Asian super ants spotted in southern England
  • Pair of rare Amur leopards born at Twycross Zoo
  • Jellyfish may Set Record in Wales
  • UK consumers paying more for technology products than US consumers
  • KZero report: Sales of VR headsets to touch 83 million by 2018