Novel Way to Produce Cloned Human Cell Lines Found

In 1996, researchers in Scotland stunned the world by announcing about Dolly, the first clone of a mammal. Since then, researchers across the world have been trying to replicate the process in humans.

It has been found that finally scientists have found a way, but a different one, to produce cloned human cell lines. The new way skips a step that requires a human egg cell making some people find the entire process less fraught.

Last year, researchers in Oregon carried out the study using DNA of infants. Robert Lanza, Chief Scientific Officer at Advanced Cell Technology, and his colleagues, including Young Gie Chung at the CHA Stem Cell Institute in Seoul, Korea explained about the success.

Firstly, they took nuclear DNA from skin cells of a middle-aged man and were injected into human eggs donated by four women. Before injecting the man's nuclear DNA, women's nuclear DNA was from these eggs.

Researchers said they also took the genetic material from the skin cells of an elderly man. "What we show for the first time is that you can actually take skin cells, from a middle-aged 35-year-old male, but also from an elderly, 75-year-old male", said Lanza.

In the second step, they injected the DNA from the first process into 77 human egg cells. In this process, researchers were able to come up with viable cells having DNA from one or the other man. These cells were capable of getting divided indefinitely.

This meant that from vials of those cells, scientists were able to grow as many cells as they want. These cells are called as embryonic stem cells due to their appearance. Researchers said with coaxing can make these cells to be introduced in any form of human cell like nerve, heart, liver and pancreas.


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