Oral Fixed-Dose Therapy for VTE Proved Safe and Effective
A multinational trial was carried out by a group of researchers from University of Perugia in Italy about an oral fixed-dose therapy. The therapy included Xa inhibitor apixaban (Eliquis) which was meant to treat venous thromboembolism (VTE).
VTE is said to be quite a dangerous form of vascular death. Available treatments for VTE include enoxaparin and warfarin. The novel treatment apixaban is said to be the first-line treatment for VTE.
It has been said so as other conventional treatments have one or the other problems. In order to know the efficacy of the treatment, the study researchers enrolled 5,400 adult patients at 358 centers in 28 different countries.
Patients were randomly assigned to have apixaban. For the first week, patients were given 10 mg BID and 5 mg BID was given for six months. Those who were at conventional treatment received enoxaparin for five days and warfarin was given for six months.
The study, which has been published in the New England Journal of Medicine, has found that the new treatment led to a recurrent rate of 2.3% at six months. But conventional treatment led to 2.7% at six months.
"More information is needed on reversal strategies, monitoring ... approaches to treatment failure, comparisons of adherence to treatment among new drugs and warfarin, and formal cost-effectiveness analyses", said study researchers.
French President Emmanuel Macron invited the U.S. President Donald Trump for Bastille Day celebrations. The White House has confirmed that President Trump will be travel to France next for the event.
Global markets registered strong start for the week with oil prices recovering and Italian banks supporting European indices. Italian authorities said that they are ready to spend 17 billion Euros to deal with closure of two big banks in Italy.
An AirAsia flight returned to Perth 90 minutes after takeoff due to single engine failure. The flight for Kuala Lumpur returned due to technical issue and landed safely in Perth at 10 am.
Microsoft has confirmed that some part of Windows 10 source code has leaked online. Some of the leaked source code was posted to Beta Archive this week. Beta Archive website keeps track of Microsoft Windows releases.
Google will stop scanning content of emails in future for serving advertisements to users based on content of their emails. Google has been criticized for this controversial advertising technique by privacy advocates.
Austrian government’s plan to offer Euro 1,000 to migrants to return home has found limited number of takers. As per Interior Ministry data, 427 migrants have accepted the offer.